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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
METHACHOLINE

METHACHOLINE


ATC V04CX03

BRONCHOCONSTRICTOR AGENT
RESPIRATORY SYSTEM
CHOLINERGIC
INHALATION DIAGNOSTIC CHALLENGE (SUBJECT WITH ASTHM ARE MORE SENSITIVE THAN HEALTHY SUBJECTS)
MORE SLOWLY HYDROLYZED BY ACETYLCHOLINESTERASES THAN ACETYLCHOLINE
ACETYLCHOLINE ANALOG THAT INDUCES BRONCHOCONSTRICTION

INHALATION

SOLUBILITY SOLUBLE IN WATER

MUSCARINIC ACETYLCHOLINE RECEPTOR M3 AGONIST CHEMBL245 MUSCARINIC ACETYLCHOLINE RECEPTOR M3 P20309 MUSCARINIC ACETYLCHOLINE RECEPTOR M3 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTORANSM (in French)

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