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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ISONIAZID
| ISONIAZID |
ANTIINFECTIVES | ORAL INJECTION | Cmax 22.5 MICROMOLAR Tmax 1.5 HOUR F 100 PERCENT VD 53.3 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 24.02 LITER / HOUR HT 2.8 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | CATALASE PEROXIDASE (KATG) PDB 4PAE (CRYSTAL STRUCTURE OF CATALASE-PEROXIDASE (KATG) W78F MUTANT FROM SYNECHOCOCCUS ELONGATUS PCC7942) LIGAND CODE = NIZ (link to the list of PDB complexes) Download experimental 3D coordinates of NIZ with added hydrogens | Enoyl-acyl-carrier-protein reductase NADH UNIPROT P9WGR1 inhA more at DrugCentral | EMA | |||
