FLURBIPROFEN | FLURBIPROFEN | ATC M01AE09 ATC M02AA19 ATC R02AX01 ATC S01BC04
MUSCULO-SKELETAL SYSTEM ANALGESICS NSAID ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL CYCLOOXYGENASE INHIBITORS | ORAL OPHTHALMIC | Cmax 57 MICROMOLAR Tmax 2 HOUR F 96 PERCENT VD 7.8 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 1.08 LITER / HOUR (EQN) HT 5 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | PROSTAGLANDIN G/H SYNTHASE 1 PROSTAGLANDIN G/H SYNTHASE 2 PDB 3RR3 (STRUCTURE OF (R)-FLURBIPROFEN BOUND TO MCOX-2) LIGAND CODE = FLR (link to the list of PDB complexes) Download experimental 3D coordinates of FLR with added hydrogens | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |