| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMINOGLUTETHIMIDE DISCONTINUED
| AMINOGLUTETHIMIDE | ANTINEOPLASTIC | ORAL | Cmax 25.4 MICROMOLAR Tmax 1.5 HOUR F 100 PERCENT HT 12.5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | CYTOCHROME P450 | Aromatase UNIPROT P11511 CYP19A1 -- Cholesterol side-chain cleavage enzyme, mitochondrial UNIPROT P05108 CYP11A1 more at DrugCentral | EMA | |||
