Cheminformatic Tools and Databases for Pharmacology

session 92367 - Total of 1 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DOBUTAMINE

DOBUTAMINE


ATC C01CA07

CARDIOVASCULAR
CARDIOTONIC
ADRENERGIC BETA AGONISTS
SYMPATHOMIMETIC
CATECHOLAMINE

INJECTION

Cmax 332 NANOMOLAR

VD 13 LITER

Cl 249 LITER / HOUR

HT 0.033 HOUR

BETA-1 ADRENERGIC RECEPTOR
CATECHOL O-METHYLTRANSFERASE (COMT)

PDB 2Y00 (TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND PARTIAL AGONIST DOBUTAMINE (CRYSTAL DOB92))

LIGAND CODE = Y00 (link to the list of PDB complexes)

Download experimental 3D coordinates of Y00 with added hydrogens

BETA-2 ADRENERGIC RECEPTOR AGONIST CHEMBL210 BETA-2 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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