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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LUMEFANTRINE

LUMEFANTRINE


ATC P01BF01

ANTIPARASITIC
ANTIMALARIALS
INHIBITS HEMOZOIN FORMATION
MEMBRANE SCRAMBLING LEADING TO PHOSPHATIDYLSERINE-EXPOSURE AT THE ERYTHROCYTE SURFACE

ORAL

Cmax 14 MICROMOLAR

PPB 99.7 PERCENT

HT 101 HOUR

SOLUBILITY INSOLUBLE IN WATER

FERRIPROTOPORPHYRIN IX INHIBITOR CHEMBL613897 FERRIPROTOPORPHYRIN IX PLASMODIUM FALCIPARUMANSM (in French)

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