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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BUPIVACAINE

BUPIVACAINE


ATC N01BB01
ATC N01BB51

NERVOUS SYSTEM
ANESTHETIC (LOCAL)
ACETYLCHOLINE RECEPTOR ION CHANNEL BLOCKER

INJECTION SPINAL IMPLANTATION INFILTRATION PERIARTICULAR

VD 54.6 LITER

PPB 94 PERCENT

Cl 16.7 LITER / HOUR

HT 3.1 HOUR

SOLUBILITY SOLUBLE IN WATER

ACETYLCHOLINE RECEPTOR
NMDA RECEPTOR
5HT3

SODIUM CHANNEL PROTEIN TYPE IV ALPHA SUBUNIT BLOCKER CHEMBL2072 SODIUM CHANNEL PROTEIN TYPE IV ALPHA SUBUNIT P35499 SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA HOMO SAPIENS ION CHANNEL VGC VG NAANSM (in French)

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