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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ETHOSUXIMIDE

ETHOSUXIMIDE


ATC N03AD01
ATC N03AD51

NERVOUS SYSTEM
ANTICONVULSANT
SUCCINIMIDES

ORAL

Cmax 496 MICROMOLAR

Tmax 5 HOUR

VD 45.5 LITER (65 KILOGRAM)

PPB 0 PERCENT

HT 60 HOUR

VOLTAGE-DEPENDENT CHANNEL

PDB 5OH3 (CEREBLON ISOFORM 4 FROM MAGNETOSPIRILLUM GRYPHISWALDENSE IN COMPLEX WITH ETHOSUXIMIDE)

LIGAND CODE = 9V2 (link to the list of PDB complexes)

Download experimental 3D coordinates of 9V2 with added hydrogens

VOLTAGE-GATED T-TYPE CALCIUM CHANNEL BLOCKER CHEMBL2362995 VOLTAGE-GATED T-TYPE CALCIUM CHANNEL O43497 VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1G HOMO SAPIENS ION CHANNEL VGC VG CAANSM (in French)

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