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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CHLORTHALIDONE

CHLORTHALIDONE


ATC C03BA04
ATC C03BB04
ATC C03EA06

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
SODIUM CHLORIDE SYMPORTER INHIBITORS

ORAL

F 64 PERCENT

VD 253 LITER (65 KILOGRAM)

PPB 76 PERCENT

Cl 5.8 LITER / HOUR

HT 36 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER (0.12 MILLIGRAM / MILLILITER)

SODIUM CHLORIDE SYMPORTER

THIAZIDE-SENSITIVE SODIUM-CHLORIDE COTRANSPORTER INHIBITOR CHEMBL1876 THIAZIDE-SENSITIVE SODIUM-CHLORIDE COTRANSPORTER P55017 SOLUTE CARRIER FAMILY 12 MEMBER 3 HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC12ANSM (in French)

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ChEMBL
BindingDB
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