Cheminformatic Tools and Databases for Pharmacology

session 81723 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
THIORIDAZINE

THIORIDAZINE


ATC N05AC02

NERVOUS SYSTEM
ANTIPSYCHOTIC
MANAGEMENT OF SCHIZOPHRENIC PATIENTS
ANXIOLYTIC
DOPAMINE ANTAGONISTS
PHENOTHIAZINES

ORAL

Cmax 0.55 MICROMOLAR

HT 15 HOUR

DOPAMINE RECEPTOR
5-HYDROXYTRYPTAMINE 2A RECEPTOR
ALPHA-1A ADRENERGIC RECEPTOR

PDB 4I1R (HUMAN MALT1 (CASPASE-IG3) IN COMPLEX WITH THIORIDAZINE)

LIGAND CODE = LZU (link to the list of PDB complexes)

Download experimental 3D coordinates of LZU with added hydrogens

D(2) dopamine receptor UNIPROT P14416 DRD2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |