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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DYPHYLLINE DISCONTINUED
| DYPHYLLINE | NATURAL MOLECULE (link)
RESPIRATORY | ORAL INJECTION | Cmax 67 MICROMOLAR VD 27.3 LITER (65 KILOGRAM) Cl 18.7 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | PHOSPHODIESTERASE | cGMP-inhibited 3,5-cyclic phosphodiesterase A UNIPROT Q14432 PDE3A -- cAMP-specific 3,5-cyclic phosphodiesterase 4B UNIPROT Q07343 PDE4B more at DrugCentral | EMA | |||
