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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DOXYLAMINE

DOXYLAMINE


ATC R06AA09
ATC R06AA59

RESPIRATORY
ANTIHISTAMINIC
HYPNOTIC
ANTI-ALLERGIC AGENTS
ANTIEMETICS
ANTITUSSIVE AGENTS
HISTAMINE H1 ANTAGONISTS

ORAL

Cmax 308 NANOMOLAR

Cl 11.7 LITER / HOUR (65 KILOGRAM)

HT 12.5 HOURHT 12.5 HOUR

SOLUBILITY VERY SOLUBLE IN WATER

HISTAMINE H1 RECEPTOR

Histamine H1 receptor UNIPROT P35367 HRH1

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