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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DOXYLAMINE

DOXYLAMINE


ATC R06AA09
ATC R06AA59

RESPIRATORY
ANTIHISTAMINIC
HYPNOTIC
ANTI-ALLERGIC AGENTS
ANTIEMETICS
ANTITUSSIVE AGENTS
HISTAMINE H1 ANTAGONISTS

ORAL

Cmax 308 NANOMOLAR

Cl 11.7 LITER / HOUR (65 KILOGRAM)

HT 12.5 HOURHT 12.5 HOUR

SOLUBILITY VERY SOLUBLE IN WATER

HISTAMINE H1 RECEPTOR

HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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