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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MEPHENYTOIN DISCONTINUED
| MEPHENYTOIN | NERVOUS SYSTEM | ORAL | VD 110.5 LITER (65 KILOGRAM) Cl 1.74 LITER / HOUR HT 63 HOUR (PMID4032286) | NA+ CHANNELS (NAV) | Sodium channel alpha subunit UNIPROT P35498 SCN1A more at DrugCentral | EMA | |||
