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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PENTOBARBITAL
| PENTOBARBITAL | NERVOUS SYSTEM | ORAL INJECTION RECTAL | VD 59 LITER (65 KILOGRAM) PPB 61 PERCENT Cl 1.83 LITER / HOUR (65 KILOGRAM) HT 22 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | GAMMA-AMINOBUTYRIC-ACID RECEPTOR | Gamma-aminobutyric acid receptor subunit beta-3 UNIPROT P28472 GABRB3 -- GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1 more at DrugCentral | EMA | |||
