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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRAMOXINE
| PRAMOXINE | DERMATOLOGICALS | TOPICAL | PDB 4Y0Q (BOVINE BETA-LACTOGLOBULIN COMPLEX WITH PRAMOCAINE CRYSTALLIZED FROM SODIUM CITRATE (BLG-PRM1)) LIGAND CODE = PX9 (link to the list of PDB complexes) Download experimental 3D coordinates of PX9 with added hydrogens | Sigma non-opioid intracellular receptor 1 UNIPROT Q99720 SIGMAR1 more at DrugCentral | EMA | ||||
