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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFIXIME
| CEFIXIME |
ANTIINFECTIVES | ORAL | Cmax 4.41 MICROMOLAR F 45 PERCENT VD 15.6 LITER (65 KILOGRAM) PPB 65 PERCENT Cl 3.9 LITER / HOUR (65 KILOGRAM) HT 4 HOUR | PENICILLIN-BINDING PROTEINS 1A/1B PDB 4KOU (CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH CEFIXIME) LIGAND CODE = C04 (link to the list of PDB complexes) Download experimental 3D coordinates of C04 with added hydrogens | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
