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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
IMIPENEM

IMIPENEM


ATC J01DH51

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CARBAPENEMS
INHIBITION OF CELL WALL SYNTHESIS

INTRAVENOUS INTRAMUSCULAR INJECTION

Cmax 277 MICROMOLAR

F 75 PERCENT

VD 14.8 LITER (65 KILOGRAM)

PPB 20 PERCENT

Cl 11.7 LITER / HOUR (65 KILOGRAM)

HT 1 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

PENICILLIN-BINDING PROTEIN

BACTERIAL PENICILLIN-BINDING PROTEIN INHIBITOR CHEMBL2354204 BACTERIAL PENICILLIN-BINDING PROTEIN P02918 PENICILLIN-BINDING PROTEIN 1A BACTERIA ENZYME PROTEASE SERINE UNCLASSIFIEDANSM (in French)

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