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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| IMIPENEM
| IMIPENEM | ANTIINFECTIVES | INTRAVENOUS INTRAMUSCULAR INJECTION | Cmax 277 MICROMOLAR F 75 PERCENT VD 14.8 LITER (65 KILOGRAM) PPB 20 PERCENT Cl 11.7 LITER / HOUR (65 KILOGRAM) HT 1 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | PENICILLIN-BINDING PROTEIN | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
