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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AZTREONAM

AZTREONAM


ATC J01DF01

ANTIINFECTIVES
ANTIBIOTIC
ANTI-BACTERIAL
INHIBITION OF BACTERIAL CELL WALL SYNTHESIS

INJECTION INHALATION

Cmax 1.5 MICROMOLAR

VD 12.6 LITER

PPB 60 PERCENT

Cl 5.4 LITER / HOUR

HT 1.7 HOUR

PENICILLIN-BINDING PROTEIN 3
BETA-LACTAMASE

PDB 1FR6 (BETA-LACTAMASE FROM CITROBACTER FREUNDII)

BACTERIAL PENICILLIN-BINDING PROTEIN INHIBITOR CHEMBL2354204 BACTERIAL PENICILLIN-BINDING PROTEIN P02918 PENICILLIN-BINDING PROTEIN 1A BACTERIA ENZYME PROTEASE SERINE UNCLASSIFIEDANSM (in French)

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