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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMDINOCILLIN DISCONTINUED (is an active metabolite)
| AMDINOCILLIN | ANTIINFECTIVES | INJECTION | VD 24 LITER (65 KILOGRAM) PPB 25 PERCENT Cl 24 LITER / HOUR (65 KILOGRAM) HT 1.1 HOUR | PENICILLIN-BINDING PROTEIN 2B PDB 6TIX (CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 2 FROM YERSINIA PESTIS IN COMPLEX WITH MECILLINAM) LIGAND CODE = DH4 (link to the list of PDB complexes) Download experimental 3D coordinates of DH4 with added hydrogens | Peptidoglycan D,D-transpeptidase MrdA UNIPROT P0AD65 mrdA more at DrugCentral | EMA | |||
