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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PIPERACILLIN

PIPERACILLIN


ATC J01CA12
ATC J01CR05

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
PENICILLINS

INJECTION

Cmax 0.57 MILLIMOLAR

Tmax 0.5 HOUR

VD 17.5 LITER (65 KILOGRAM)

PPB 16 PERCENT

Cl 15.6 LITER / HOUR (65 KILOGRAM)

HT 0.96 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

PENICILLIN-BINDING PROTEINS 1A/1B

PDB 3Q07 (CTX-M-9 S70G IN COMPLEX WITH PIPERACILLIN)

LIGAND CODE = WPP (link to the list of PDB complexes)

Download experimental 3D coordinates of WPP with added hydrogens

BACTERIAL PENICILLIN-BINDING PROTEIN INHIBITOR CHEMBL2354204 BACTERIAL PENICILLIN-BINDING PROTEIN P02918 PENICILLIN-BINDING PROTEIN 1A BACTERIA ENZYME PROTEASE SERINE UNCLASSIFIEDANSM (in French)

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