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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMIKACIN
| AMIKACIN |
ANTIINFECTIVES | INJECTION INHALATION | Cmax 65 MICROMOLAR (500 MILLIGRAM) VD 10 LITER (65 KILOGRAM) PPB 12 PERCENT Cl 4.3 LITER / HOUR (65 KILOGRAM) HT 2.4 HOUR | 30S RIBOSOMAL PROTEIN S12 PDB 4P20 (CRYSTAL STRUCTURES OF THE BACTERIAL RIBOSOMAL DECODING SITE COMPLEXED WITH AMIKACIN) LIGAND CODE = AKN (link to the list of PDB complexes) Download experimental 3D coordinates of AKN with added hydrogens | Unknown more at DrugCentral | EMA | |||
