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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VIDARABINE DISCONTINUED
| VIDARABINE | ANTIVIRAL | OPHTHALMIC INJECTION | ADENOSINE DEAMINASE THYMIDINE KINASE DNA PURINE NUCLEOSIDE PHOSPHORYLASE DNA POLYMERASE PDB 1PW7 (CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-ARABINOFURANOSYLADENINE AND SULFATE, PHOSPHATE) LIGAND CODE = RAB (link to the list of PDB complexes) Download experimental 3D coordinates of RAB with added hydrogens | DNA polymerase catalytic subunit UNIPROT P04293 more at DrugCentral | EMA | ||||
