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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFAZOLIN
| CEFAZOLIN | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 407 MICROMOLAR (1 GRAM) Tmax 0.25 HOUR (2 GRAM) VD 7.8 LITER (65 KILOGRAM) PPB 82 PERCENT Cl 3.4 LITER / HOUR HT 1.8 HOUR | PENICILLIN-BINDING PROTEINS 1A/1B PDB 8YXA (CRYSTAL STRUCTURE OF THE HSA COMPLEX WITH CEFAZOLIN AND MYRISTATE) LIGAND CODE = X56 (link to the list of PDB complexes) Download experimental 3D coordinates of X56 with added hydrogens | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
