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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PYRILAMINE DISCONTINUED
| PYRILAMINE |
RESPIRATORY SYSTEM | OPHTHALMIC ORAL | HISTAMINE RECEPTOR PDB 8X63 (CRYOEM STRUCTURE OF THE HISTAMINE H1 RECEPTOR-BRIL, ANTI BRIL FAB COMPLEX WITH MEPYRAMINE) LIGAND CODE = Y5E (link to the list of PDB complexes) Download experimental 3D coordinates of Y5E with added hydrogens | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | ||||
