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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ERGOCALCIFEROL

ERGOCALCIFEROL


ATC A11CC01

METABOLISM
VITAMIN D2
ANTIHYPOCALCEMIC AGENTS
TREATMENT OF HYPOPARATHYROIDISM AND REFRACTORY RICKETS ALSO KNOWN AS VITAMIN D RESISTANT RICKETS,AND FAMILIAL HYPOPHOSPHATEMIA
DIFFERENT METABOLIC FATES OF VITAMINS D2 AND D3 (PMID17023693)

ORAL INJECTION INTRAVENOUS

SOLUBILITY INSOLUBLE IN WATER

VITAMIN D3 RECEPTOR

PDB 3CZH (CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH VITAMIN D2)

LIGAND CODE = D2V (link to the list of PDB complexes)

Download experimental 3D coordinates of D2V with added hydrogens

Vitamin D3 receptor UNIPROT P11473 VDR

more at DrugCentral

EMA

ANSM (in French)

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Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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