e-Drug3D

965

cas 3521-62-8

CLASS

DERMATOLOGICALS
ANTIBIOTIC
ANTIBACTERIAL

ROUTE (list)

ORAL

PK parameters

MW 789.98
NB_atoms 55
XLogP 2.75
PSA 140.872
NB_HD 4
NB_HA 15
fsp3 0.93
Lipinski(0=no;1=yes) 0

FDA
NDA 050599 (pdf not found) INN (ERYTHROMYCIN ESTOLATE ; SULFISOXAZOLE ACETYL) ILOSONE SULFA (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062237 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (IVAX SUB TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050010 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (LILLY) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 061893 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (DISTA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 061894 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (LILLY) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 061895 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (DISTA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 061896 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (LILLY) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 061897 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ILOSONE (LILLY) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 062087 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (WATSON LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062162 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (BARR) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 062353 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062362 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (LIFE LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062409 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062169 (pdf not found) INN (ERYTHROMYCIN ESTOLATE) ERYTHROMYCIN ESTOLATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 1990 DISCONTINUED

e-Drug3D

964

cas 114-07-8

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL

ROUTE (list)

INJECTION OPHTHALMIC TOPICAL ORAL

PK parameters

Tmax 3 HOUR
VD 61.7 LITER (65 KILOGRAM)
Cl 21.8 LITER / HOUR (65 KILOGRAM)
PPB 90 PERCENT
t1/2 2 HOUR

TARGET 50S RIBOSOMAL PROTEIN

PDB
4M83 (ENSEMBLE REFINEMENT OF PROTEIN CRYSTAL STRUCTURE (2IYF) OF MACROLIDE GLYCOSYLTRANSFERASES OLED COMPLEXED WITH UDP AND ERYTHROMYCIN A)

Ligand code = ERY (link to the list of PDB complexes)

Download experimental 3D coordinates of ERY with added hydrogens

MW 733.92
NB_atoms 51
XLogP 1.79
PSA 145.634
NB_HD 5
NB_HA 14
fsp3 0.95
Lipinski(0=no;1=yes) 0

FDA
NDA 050370 (pdf not found) INN (ERYTHROMYCIN GLUCEPTATE) ILOTYCIN GLUCEPTATE (DISTA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050610 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PADDOCK LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061304 (pdf not found) INN (ERYTHROMYCIN STEARATE) BRISTAMYCIN (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061605 (pdf not found) INN (ERYTHROMYCIN STEARATE) ETHRIL 250 (BRISTOL MYERS SQUIBB) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061633 (pdf not found) INN (ERYTHROMYCIN) ROBIMYCIN (ROBINS AH) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061659 (pdf not found) INN (ERYTHROMYCIN) R-P MYCIN (SOLVAY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061675 (pdf not found) INN (ERYTHROMYCIN STEARATE) WYAMYCIN S (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061743 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061791 (pdf not found) INN (ERYTHROMYCIN STEARATE) PFIZER-E (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062089 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062121 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062322 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYPAR (WARNER CHILCOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062327 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062342 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062446 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMADERM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062481 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062485 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062546 (pdf not found) INN (ERYTHROMYCIN) ERYC (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062604 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062618 (pdf not found) INN (ERYTHROMYCIN) ERYC (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062648 (pdf not found) INN (ERYTHROMYCIN) ERYC 125 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062660 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062957 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050182 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROCIN (HOSPIRA) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 050368 (pdf not found) INN (ERYTHROMYCIN) ILOTYCIN (DISTA) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 060359 (label) INN (ERYTHROMYCIN STEARATE) ERYTHROCIN STEARATE (AZURITY) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 061591 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (ANI PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 061621 (label) INN (ERYTHROMYCIN) ERYTHROMYCIN (CARNEGIE) APPROVAL= AP YEAR= 1972
NDA 061505 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 061887 (pdf not found) INN (ERYTHROMYCIN STEARATE) BRISTAMYCIN (BRISTOL) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 061910 (pdf not found) INN (ERYTHROMYCIN) ILOTYCIN (DISTA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 062032 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYPAR (PARKE DAVIS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 050526 (label) INN (ERYTHROMYCIN) STATICIN (WESTWOOD SQUIBB) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 050532 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (LILLY) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 061461 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (ANI PHARMS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062290 (pdf not found) INN (ERYTHROMYCIN) ERYDERM (ARBOR PHARMS INC) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 050536 (label) INN (ERYTHROMYCIN) ERYC (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1981
NDA 060272 (pdf not found) INN (ERYTHROMYCIN) E-MYCIN (ARBOR PHARMS INC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 062338 (pdf not found) INN (ERYTHROMYCIN) ERYC (WARNER CHILCOTT LLC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 062298 (label) INN (ERYTHROMYCIN) ERY-TAB (CARNEGIE) APPROVAL= AP YEAR= 1982
NDA 062326 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062328 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062405 (pdf not found) INN (ERYTHROMYCIN) A/T/S (TARO) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062436 (pdf not found) INN (ERYTHROMYCIN) T-STAT (WESTWOOD SQUIBB) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 062447 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PADAGIS US) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 050557 (label) INN (BENZOYL PEROXIDE ; ERYTHROMYCIN) BENZAMYCIN (VALEANT INTL) APPROVAL= AP YEAR= 1984
NDA 050584 (pdf not found) INN (ERYTHROMYCIN) AKNE-MYCIN (BAUSCH) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 050593 (pdf not found) INN (ERYTHROMYCIN) ERYC SPRINKLES (HOSPIRA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 050594 (pdf not found) INN (ERYTHROMYCIN) ERYCETTE (JOHNSON AND JOHNSON) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062467 (pdf not found) INN (ERYTHROMYCIN) E-SOLVE 2 (SYOSSET) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062468 (pdf not found) INN (ERYTHROMYCIN) C-SOLVE-2 (FOUGERA PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062508 (pdf not found) INN (ERYTHROMYCIN) ERYMAX (MERZ PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062522 (pdf not found) INN (ERYTHROMYCIN) SANSAC (DOW PHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062563 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN (ELKINS SINN) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062616 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMAFAIR) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 050609 (label) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROCIN (HOSPIRA) APPROVAL= AP YEAR= 1986
NDA 050611 (label) INN (ERYTHROMYCIN) PCE (AZURITY) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 062638 (label) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROCIN (HOSPIRA) APPROVAL= AP YEAR= 1986
NDA 062746 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (CARNEGIE) APPROVAL= AP YEAR= 1986
NDA 050617 (pdf not found) INN (ERYTHROMYCIN) ERYGEL (MYLAN) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062748 (pdf not found) INN (ERYTHROMYCIN) T-STAT (WESTWOOD SQUIBB) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062825 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMOBEDIENT CNSLTG) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062586 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROCIN (ABBOTT) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062687 (pdf not found) INN (ERYTHROMYCIN) ERYTHRA-DERM (MICRO LABS) APPROVAL= AP YEAR= 1988
NDA 062999 (pdf not found) INN (ERYTHROMYCIN) E-BASE (BARR) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062993 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063098 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (BARR) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063028 (pdf not found) INN (ERYTHROMYCIN) E-BASE (BARR) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 063086 (pdf not found) INN (ERYTHROMYCIN) E-BASE (BARR) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 063179 (pdf not found) INN (ERYTHROMYCIN STEARATE) ERYTHROMYCIN STEARATE (ANI PHARMS) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 063038 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PADAGIS US) APPROVAL= AP YEAR= 1991
NDA 063107 (pdf not found) INN (ERYTHROMYCIN) EMGEL (ALTANA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 062751 (pdf not found) INN (ERYTHROMYCIN) C-SOLVE-2 (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 063211 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PADAGIS US) APPROVAL= AP YEAR= 1993
NDA 063253 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 064039 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (BAUSCH) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 064067 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 1994
NDA 064030 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (SENTISS) APPROVAL= AP YEAR= 1996
NDA 064101 (pdf not found) INN (ERYTHROMYCIN) ERYTHRO-STATIN (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064126 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PADAGIS US) APPROVAL= AP YEAR= 1996
NDA 064128 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (PHARMOBEDIENT) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064127 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (RENAISSANCE PHARMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064184 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (FOUGERA PHARMS) APPROVAL= AP YEAR= 1997
NDA 064187 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (FOUGERA PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 050769 (label) INN (BENZOYL PEROXIDE ; ERYTHROMYCIN) AKTIPAK (BIOFRONTERA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 065009 (pdf not found) INN (ERYTHROMYCIN) E-GLADES (PHARMOBEDIENT) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 065112 (pdf not found) INN (BENZOYL PEROXIDE ; ERYTHROMYCIN) ERYTHROMYCIN AND BENZOYL PEROXIDE (ENCUBE) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065320 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (FOUGERA PHARMS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 090215 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2010
NDA 065385 (pdf not found) INN (BENZOYL PEROXIDE ; ERYTHROMYCIN) ERYTHROMYCIN AND BENZOYL PEROXIDE (RISING) APPROVAL= AP YEAR= 2015
NDA 208154 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ENCUBE) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208100 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ENCUBE) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 209720 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210954 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2019
NDA 212015 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (TORRENT) APPROVAL= AP YEAR= 2020
NDA 211086 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (EXELA PHARMA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213628 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2021
NDA 214549 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021
NDA 211975 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (TORRENT) APPROVAL= AP YEAR= 2021
NDA 215290 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (NEXUS) APPROVAL= AP YEAR= 2022
NDA 216066 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALKEM LABS LTD) APPROVAL= AP YEAR= 2022
NDA 212693 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2023
NDA 215440 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 215661 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ALEMBIC) APPROVAL= AP YEAR= 2023
NDA 216761 (pdf not found) INN (ERYTHROMYCIN LACTOBIONATE) ERYTHROMYCIN LACTOBIONATE (GLAND) APPROVAL= AP YEAR= 2024
NDA 219691 (pdf not found) INN (ERYTHROMYCIN) ERYTHROMYCIN (ABON PHARMS LLC) APPROVAL= AP YEAR= 2025