6
DISCONTINUED
INN
DESOXYCORTICOSTERONE PIVALATE
HORMONES
ANTI-ADDISON AGENTS
ADRENOCORTICAL STEROID
PRECURSOR OF ALDOSTERONE
SUBSTRATE OF ALDOSTERONE SYNTHASE (CYTOCHROME P450 CYP11B2)
INJECTION
ATC code
H02AA03
INSOLUBLE IN WATER
PDB
4DVQ (HUMAN ALDOSTERONE SYNTHASE PMID23322723)
Ligand code = - (link to the list of PDB complexes)
Download experimental 3D coordinates of - with added hydrogens
Mineralocorticoid receptor UNIPROT P08235 NR3C2
Formula:
C26H38O4
Calculated chemical properties:
NB_atoms 30
XLogP 5.29
PSA 58.388
NB_HD 0
NB_HA 4
fsp3 0.81
Lipinski(0=no;1=yes) 0
NDA 008822 (pdf not found) INN (DESOXYCORTICOSTERONE PIVALATE) PERCORTEN (NOVARTIS) APPROVAL= - YEAR= 0 DISCONTINUED
1791
HORMONES
ADRENOCORTICAL STEROID
PRECURSOR OF ALDOSTERONE
SUBSTRATE OF ALDOSTERONE SYNTHASE (CYTOCHROME P450 CYP11B2)
-
ATC code
H02AA03
PDB
2AA7 (MINERALOCORTICOID RECEPTOR WITH BOUND DEOXYCORTICOSTERONE)
Ligand code = 1CA (link to the list of PDB complexes)
Download experimental 3D coordinates of 1CA with added hydrogens
Mineralocorticoid receptor UNIPROT P08235 NR3C2
Formula:
C21H30O3
Calculated chemical properties:
NB_atoms 24
XLogP 3.70
PSA 54.086
NB_HD 1
NB_HA 3
fsp3 0.81
Lipinski(0=no;1=yes) 1
-