e-Drug3D

223

cas 2921-57-5

CLASS

GLUCOCORTICOID
ANTIINFLAMMATORY

ROUTE (list)

INJECTION

PK parameters

MW 473.52
NB_atoms 34
XLogP 0.88
PSA 124.644
NB_HD 2
NB_HA 8
fsp3 0.69
Lipinski(0=no;1=yes) 1

FDA
NDA 086953 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087030 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087812 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087813 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087851 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087852 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088523 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088524 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088677 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088678 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088679 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089186 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089188 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089264 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089265 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089266 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089267 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011856 (label) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) SOLU-MEDROL (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1959
NDA 085852 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085853 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085854 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085855 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086906 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ELKINS SINN) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087535 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE (ORGANON USA INC) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088676 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 089143 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089144 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089187 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089189 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089173 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 089174 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 089573 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (ABBOTT) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 089574 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (ABBOTT) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 089575 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (ABBOTT) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 089576 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (ABBOTT) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 081266 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 081267 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 081268 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 040583 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2004
NDA 040612 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2004
NDA 040664 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 040665 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 040641 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (BEDFORD LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040662 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (BEDFORD LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040709 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (BEDFORD LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040793 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA INC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 040827 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) A-METHAPRED (HOSPIRA INC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 040888 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2011
NDA 207667 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 202691 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (HIKMA) APPROVAL= AP YEAR= 2016
NDA 207549 (label) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (AMNEAL) APPROVAL= AP YEAR= 2016
NDA 212396 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (TIANJIN KINGYORK) APPROVAL= AP YEAR= 2021
NDA 203125 (pdf not found) INN (METHYLPREDNISOLONE SODIUM SUCCINATE) METHYLPREDNISOLONE SODIUM SUCCINATE (HIKMA) APPROVAL= AP YEAR= 2022

e-Drug3D

222

cas 83-43-2

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTI-INFLAMMATORY AGENTS

ROUTE (list)

ORAL OPHTHALMIC

PK parameters

VD 78 LITER (65 KILOGRAM)
Cl 23.8 LITER / HOUR (65 KILOGRAM)
PPB 77 PERCENT
t1/2 2.3 HOUR

MW 374.46
NB_atoms 27
XLogP 1.80
PSA 85.658
NB_HD 3
NB_HA 5
fsp3 0.73
Lipinski(0=no;1=yes) 1

FDA
NDA 060645 (pdf not found) INN (METHYLPREDNISOLONE ; NEOMYCIN SULFATE) NEO-MEDROL (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085650 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011153 (label) INN (METHYLPREDNISOLONE) MEDROL (PFIZER) APPROVAL= AP YEAR= 1957 NEWMOLECULARENTITY
NDA 087341 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (RISING) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086159 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086161 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088497 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 089207 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (PAR PHARM) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089208 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (PAR PHARM) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089209 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (PAR PHARM) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040189 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (JUBILANT CADISTA) APPROVAL= AP YEAR= 1997
NDA 040194 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (SANDOZ) APPROVAL= AP YEAR= 1997
NDA 040232 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (WATSON LABS) APPROVAL= AP YEAR= 1997
NDA 040183 (label) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (PH HEALTH) APPROVAL= AP YEAR= 1998
NDA 204072 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (TIANJIN TIANYAO) APPROVAL= AP YEAR= 2018
NDA 206751 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 209097 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (CHARTWELL RX) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210985 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 212262 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (PRAXGEN) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 207481 (pdf not found) INN (METHYLPREDNISOLONE) METHYLPREDNISOLONE (AMNEAL) APPROVAL= AP YEAR= 2021 DISCONTINUED