e-Drug3D

2185
MILSAPERIDONE


INN
MILSAPERIDONE

(is an active metabolite) (has an active metabolite)

cas 501373-88-2
CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
BIPOLAR I DISORDER
DOPAMINE TYPE 2 (D2) AND SEROTONIN TYPE 2 (5-HT2) ANTAGONISM
ROUTE (list)

ORAL

ATC code
PK parameters

Tmax 4 HOUR
VD 2029 LITER
Cl 50.5 LITER / HOUR
PPB 92 PERCENT
t1/2 26 HOUR

 Target

TARGET DOPAMINE TYPE 2 RECEPTOR
SEROTONIN TYPE 2 (5-HT2) RECEPTOR

 DrugCentral

-

 Download SDF file Benzenemethanol, 4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-alpha-methyl-, (alphaS)-

Formula:
C24H29FN2O4

Calculated chemical properties:

MW 428.49
NB_atoms 31
XLogP 4.68
PSA 71.824
NB_HD 1
NB_HA 6
fsp3 0.46
Lipinski(0=no;1=yes) 1

FDA
NDA 220358 (label) INN (MILSAPERIDONE) BYSANTI (VANDA PHARMS INC) APPROVAL= AP YEAR= 2026 NEWMOLECULARENTITY

 Other links:

PubChem
ChemicalProbes

U.S. repository of Clinical Trials

VigiAccess
SIDER side effects

ChemSynthesis
Patent@SureChEMBL
e-Drug3D

2197
M ILOPERIDONE


INN
ILOPERIDONE

(is an active metabolite)

cas 475110-48-6
CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
BIPOLAR I DISORDER
DOPAMINE TYPE 2 (D2) AND SEROTONIN TYPE 2 (5-HT2) ANTAGONISM
ROUTE (list)

-

ATC code

N05AX14
PK parameters

Tmax 6 HOUR
PPB 92 PERCENT
t1/2 23 HOUR

 Target

TARGET DOPAMINE TYPE 2 RECEPTOR
SEROTONIN TYPE 2 (5-HT2) RECEPTOR

 DrugCentral

-

 Download SDF file Benzoic acid, 4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy- (9CI, ACI)

Formula:
C23H25FN2O5

Calculated chemical properties:

MW 427.44
NB_atoms 31
XLogP 2.99
PSA 87.234
NB_HD 0
NB_HA 7
fsp3 0.39
Lipinski(0=no;1=yes) 1

FDA
-

 Other links:

PubChem
ChemicalProbes

U.S. repository of Clinical Trials

VigiAccess
SIDER side effects

ChemSynthesis
Patent@SureChEMBL