e-Drug3D

210

cas 51-98-9

CLASS

GENITO
PROGESTIN
CONTRACEPTIVE
RAPIDLY HYDROLYZED IN NORETHINDRONE

ROUTE (list)

ORAL TRANSDERMAL INTRAMUSCULAR

PK parameters

MW 340.44
NB_atoms 25
XLogP 4.06
PSA 41.224
NB_HD 0
NB_HA 3
fsp3 0.73
Lipinski(0=no;1=yes) 1

FDA
NDA 016723 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORLESTRIN 28 1/50 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012184 (pdf not found) INN (NORETHINDRONE ACETATE) NORLUTATE (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016749 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORLESTRIN 21 1/50 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016766 (pdf not found) INN (ETHINYL ESTRADIOL ; FERROUS FUMARATE ; NORETHINDRONE ACETATE) NORLESTRIN FE 1/50 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016852 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORLESTRIN 21 2.5/50 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016854 (pdf not found) INN (ETHINYL ESTRADIOL ; FERROUS FUMARATE ; NORETHINDRONE ACETATE) NORLESTRIN FE 2.5/50 (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017354 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LOESTRIN FE 1/20 (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 017355 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LOESTRIN FE 1.5/30 (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 017875 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LOESTRIN 21 1.5/30 (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 017876 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LOESTRIN 21 1/20 (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 018405 (label) INN (NORETHINDRONE ACETATE) AYGESTIN (DURAMED RES) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 020130 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) ESTROSTEP 21 (APIL) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020870 (label) INN (ESTRADIOL ; NORETHINDRONE ACETATE) COMBIPATCH (NOVEN PHARMS INC) APPROVAL= AP YEAR= 1998
NDA 020907 (label) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ACTIVELLA (AMNEAL) APPROVAL= AP YEAR= 1998
NDA 021065 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) FEMHRT (APIL) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 021102 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) FEMHRT (WARNER CHILCOTT) APPROVAL= AP YEAR= 1999 NEWAPPLICATION
NDA 021103 (label) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ACTIVELLA (NOVO NORDISK) APPROVAL= AP YEAR= 2000 NEWAPPLICATION DISCONTINUED
NDA 075548 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) MICROGESTIN FE 1.5/30 (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075647 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) MICROGESTIN FE 1/20 (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075951 (label) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (BARR) APPROVAL= AP YEAR= 2001
NDA 076064 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) JUNEL FE 1.5/30 (BARR) APPROVAL= AP YEAR= 2003
NDA 076081 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) JUNEL FE 1/20 (BARR) APPROVAL= AP YEAR= 2003
NDA 076380 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) JUNEL 1/20 (BARR LABS) APPROVAL= AP YEAR= 2003
NDA 076381 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) JUNEL 1.5/30 (BARR) APPROVAL= AP YEAR= 2003
NDA 077075 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) GILDESS FE 1.5/30 (PH HEALTH) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077077 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) GILDESS FE 1/20 (PH HEALTH) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021871 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LOESTRIN 24 FE (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 022001 (label) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ACTIVELLA (NOVO NORDISK INC) APPROVAL= AP YEAR= 2006 NEWAPPLICATION
NDA 076105 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) TRI-LEGEST FE (BARR) APPROVAL= AP YEAR= 2007
NDA 076405 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) TRI-LEGEST 21 (BARR) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078324 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (BRECKENRIDGE PHARM) APPROVAL= AP YEAR= 2008
NDA 076221 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (BARR LABS INC) APPROVAL= AP YEAR= 2009
NDA 078267 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 076629 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 022501 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LO LOESTRIN FE (APIL) APPROVAL= AP YEAR= 2010
NDA 079193 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (BARR) APPROVAL= AP YEAR= 2010
NDA 091090 (pdf not found) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 200275 (pdf not found) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2012
NDA 200747 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 203696 (label) INN (LEUPROLIDE ACETATE ; NORETHINDRONE ACETATE) LUPANETA PACK (ABBVIE ENDOCRINE) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 091453 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LARIN FE 1.5/30 (NOVAST LABS) APPROVAL= AP YEAR= 2013
NDA 091454 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LARIN FE 1/20 (NOVAST LABS) APPROVAL= AP YEAR= 2013
NDA 202771 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2013
NDA 202772 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2013
NDA 202995 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LARIN 1/20 (NOVAST LABS) APPROVAL= AP YEAR= 2013
NDA 203667 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) MINASTRIN 24 FE (APIL) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 204426 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) TAYTULLA (APIL) APPROVAL= AP YEAR= 2013
NDA 204654 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LO MINASTRIN FE (APIL) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 090938 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (BARR LABS) APPROVAL= AP YEAR= 2014
NDA 090293 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) GILDESS 24 FE (PH HEALTH) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202742 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202996 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LARIN 1.5/30 (NOVAST LABS) APPROVAL= AP YEAR= 2014
NDA 203113 (pdf not found) INN (NORETHINDRONE ACETATE ; ETHINYL ESTRADIOL ; FERROUS FUMARATE) LO-BLISOVI FE (LUPIN LTD) APPROVAL= TA YEAR= 2014
NDA 202741 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2015
NDA 202770 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2015
NDA 202994 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LARIN 24 FE (NOVAST LABS) APPROVAL= AP YEAR= 2015
NDA 203038 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2015
NDA 091398 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) BLISOVI 24 FE (LUPIN) APPROVAL= AP YEAR= 2015
NDA 201584 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) BLISOVI FE 1/20 (LUPIN) APPROVAL= AP YEAR= 2015
NDA 201585 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) BLISOVI FE 1.5/30 (LUPIN) APPROVAL= AP YEAR= 2015
NDA 204213 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) FYAVOLV (LUPIN) APPROVAL= AP YEAR= 2015
NDA 203339 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) AMABELZ (LUPIN) APPROVAL= AP YEAR= 2016
NDA 203435 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LERIBANE (NOVAST LABS) APPROVAL= AP YEAR= 2016
NDA 204236 (pdf not found) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 205049 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206287 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) MIBELAS 24 FE (LUPIN) APPROVAL= AP YEAR= 2016
NDA 206969 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2016
NDA 208097 (pdf not found) INN (NORETHINDRONE ACETATE ; ETHINYL ESTRADIOL ; ETHINYL ESTRADIOL ; FERROUS FUMARATE) NORETHINDRONE ACETATE; ETHINYL ESTRADIOL; ETHINYL ESTRADIOL; FERROUS FUMARATE (GLENMARK PHARMS LTD) APPROVAL= TA YEAR= 2016
NDA 205278 (pdf not found) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (XIROMED) APPROVAL= AP YEAR= 2016
NDA 207259 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 208661 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LO LARIN FE (NOVAST LABS LTD) APPROVAL= TA YEAR= 2016
NDA 207514 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 206120 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207260 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207261 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (XIROMED) APPROVAL= AP YEAR= 2017
NDA 207504 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) AUROVELA 24 FE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 207505 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) AUROVELA FE 1/20 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 207506 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) AUROVELA 1/20 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 207580 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) AUROVELA FE 1.5/30 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 207581 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) AUROVELA 1.5/30 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 204847 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) HAILEY 24 FE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2017
NDA 206597 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) HAILEY FE 1/20 (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2017
NDA 210369 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2017
NDA 208639 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (APOTEX) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210233 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (NAARI PTE) APPROVAL= AP YEAR= 2018
NDA 205069 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2018
NDA 206490 (pdf not found) INN (NORETHINDRONE ACETATE) NORETHINDRONE ACETATE (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2018
NDA 209031 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) HAILEY FE 1.5/30 (GLENMARK SPECLT) APPROVAL= AP YEAR= 2018
NDA 209297 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) HAILEY 1.5/30 (GLENMARK SPECLT) APPROVAL= AP YEAR= 2018
NDA 209609 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2018
NDA 210612 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ESTRADIOL AND NORETHINDRONE ACETATE (NOVAST LABS) APPROVAL= AP YEAR= 2019
NDA 202962 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) CHABELINA FE (NOVAST LABS) APPROVAL= AP YEAR= 2020
NDA 210087 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) FINZALA (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2020
NDA 213388 (label) INN (ELAGOLIX SODIUM ; ESTRADIOL ; NORETHINDRONE ACETATE ; ELAGOLIX SODIUM) ORIAHNN COPACKAGED (ABBVIE) APPROVAL= AP YEAR= 2020
NDA 212706 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) MERZEE (WILSHIRE PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 213317 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) GEMMILY (XIROMED) APPROVAL= AP YEAR= 2020
NDA 214292 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214846 (label) INN (ESTRADIOL ; NORETHINDRONE ACETATE ; RELUGOLIX) MYFEMBREE (SUMITOMO PHARMA AM) APPROVAL= AP YEAR= 2021
NDA 213901 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 213418 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2022
NDA 214729 (pdf not found) INN (ESTRADIOL ; NORETHINDRONE ACETATE) ETYQA (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 216558 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) OSHIH (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 218718 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) FEMLYV (MILLICENT MFG PR) APPROVAL= AP YEAR= 2024
NDA 217650 (pdf not found) INN (ELAGOLIX ; ESTRADIOL ; NORETHINDRONE ACETATE) SHEUR (TEVA PHARM) APPROVAL= TA YEAR= 2025
NDA 219324 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ACETATE) LO JUNEL FE (TEVA PHARMS INC) APPROVAL= AP YEAR= 2026

e-Drug3D

209

cas 68-22-4

CLASS

GENITO
PROGESTIN
CONTRACEPTIVES

ROUTE (list)

ORAL

PK parameters

F 64 PERCENT
Tmax 1.83 HOUR
VD 260 LITER (65 KILOGRAM)
Cl 26 LITER / HOUR (65 KILOGRAM)
PPB 61 PERCENT
t1/2 8.51 HOUR

TARGET PROGESTERONE RECEPTOR

PDB
2W8Y (RU486 BOUND TO THE PROGESTERONE RECEPTOR IN A DESTABILIZED AGONISTIC CONFORMATION)

Ligand code = NDR (link to the list of PDB complexes)

Download experimental 3D coordinates of NDR with added hydrogens

MW 298.41
NB_atoms 22
XLogP 3.49
PSA 37.282
NB_HD 1
NB_HA 2
fsp3 0.75
Lipinski(0=no;1=yes) 1

FDA
NDA 010895 (pdf not found) INN (NORETHINDRONE) NORLUTIN (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016715 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) ORTHO-NOVUM 1/80 21 (ORTHO MCNEIL PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012728 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) ORTHO-NOVUM 10-21 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1962 DISCONTINUED
NDA 013625 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORINYL 1+50 21-DAY (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 016659 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORINYL 1+50 28-DAY (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 016709 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) ORTHO-NOVUM 1/50 28 (ORTHO MCNEIL JANSSEN) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 016724 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORINYL 1+80 21-DAY (GD SEARLE LLC) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 016725 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORINYL 1+80 28-DAY (GD SEARLE LLC) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 016954 (label) INN (NORETHINDRONE) MICRONOR (JANSSEN PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 017060 (pdf not found) INN (NORETHINDRONE) NOR-QD (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 1973
NDA 017488 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) MODICON 21 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017489 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ORTHO-NOVUM 1/35-21 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017565 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORINYL 1+35 21-DAY (ALLERGAN) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017566 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) BREVICON 21-DAY (ALLERGAN) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 017576 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) OVCON-50 (WARNER CHILCOTT LLC) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017716 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) OVCON-35 (WARNER CHILCOTT LLC) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 017735 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) MODICON 28 (JANSSEN PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 017743 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) BREVICON 28-DAY (ALLERGAN) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 017919 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ORTHO-NOVUM 1/35-28 (JANSSEN PHARMS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 018127 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) OVCON-35 (WARNER CHILCOTT) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018128 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) OVCON-50 (WARNER CHILCOTT) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 017948 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE ; FERROUS FUMARATE) NORMINEST FE (GD SEARLE LLC) APPROVAL= AP YEAR= 1978
NDA 018354 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ORTHO-NOVUM 10/11-21 (ORTHO MCNEIL JANSSEN) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018977 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) TRI-NORINYL 21-DAY (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1984
NDA 018985 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ORTHO-NOVUM 7/7/7-21 (JANSSEN PHARMS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 019004 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ORTHO-NOVUM 7/14-21 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 018926 (label) INN (ETHINYL ESTRADIOL ; FERROUS FUMARATE ; NORETHINDRONE) NORQUEST FE (PFIZER) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070684 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON LABS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070685 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON PHARMS TEVA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070686 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070687 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON LABS TEVA) APPROVAL= AP YEAR= 1987
NDA 071541 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) N.E.E. 1/35 21 (LPI) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 071542 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) N.E.E. 1/35 28 (LPI) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070758 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORETHINDRONE AND MESTRANOL (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 070759 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORETHINDRONE AND MESTRANOL (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071043 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL 10/11 (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071044 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL 10/11 (WATSON LABS TEVA) APPROVAL= AP YEAR= 1988
NDA 071480 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHIN 1/35E-21 (WATSON PHARMS TEVA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071481 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHIN 1/35E-28 (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071539 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORETHIN 1/50M-21 (HERITAGE PHARMA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071540 (pdf not found) INN (MESTRANOL ; NORETHINDRONE) NORETHIN 1/50M-28 (HERITAGE PHARMA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 071545 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORCEPT-E 1/35 21 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 071546 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORCEPT-E 1/35 28 (ORTHO MCNEIL PHARM) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 071041 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL 7/14 (WATSON LABS TEVA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 071042 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL 7/14 (WATSON LABS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 072692 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORTREL 0.5/35-21 (BARR) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 072693 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORTREL 1/35-21 (BARR) APPROVAL= AP YEAR= 1992
NDA 072694 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) GENCEPT 10/11-21 (BARR) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 072695 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORTREL 0.5/35-28 (BARR LABS) APPROVAL= AP YEAR= 1992
NDA 072696 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORTREL 1/35-28 (BARR LABS) APPROVAL= AP YEAR= 1992
NDA 072697 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) GENCEPT 10/11-28 (BARR LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 075478 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORTREL 7/7/7 (BARR) APPROVAL= AP YEAR= 2002
NDA 076177 (pdf not found) INN (NORETHINDRONE) CAMILA (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2002
NDA 076225 (pdf not found) INN (NORETHINDRONE) ERRIN (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2002
NDA 021490 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) FEMCON FE (APIL) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076198 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) BALZIVA-21 (BARR) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076238 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) BALZIVA-28 (BARR) APPROVAL= AP YEAR= 2004
NDA 076783 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ARANELLE (BARR) APPROVAL= AP YEAR= 2004
NDA 076393 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON LABS) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 078323 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON LABS) APPROVAL= AP YEAR= 2010
NDA 078379 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (WATSON LABS) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 078965 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (BARR) APPROVAL= AP YEAR= 2010
NDA 090454 (pdf not found) INN (NORETHINDRONE) HEATHER (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 076337 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) CYCLAFEM 1/35 (PH HEALTH) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 076338 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) CYCLAFEM 7/7/7 (PH HEALTH) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091209 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 022573 (label) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (TEVA BRANDED PHARM) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 078892 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 090538 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) BRIELLYN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2011
NDA 090946 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) DASETTA 7/7/7 (NOVAST LABS LTD) APPROVAL= AP YEAR= 2011
NDA 090947 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) PHILITH (NOVAST LABS LTD) APPROVAL= AP YEAR= 2011
NDA 090948 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) DASETTA 1/35 (NOVAST LABS LTD) APPROVAL= AP YEAR= 2011
NDA 091325 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (LUPIN LTD) APPROVAL= AP YEAR= 2011
NDA 091634 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ALYACEN 1/35 (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2012
NDA 091636 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) ALYACEN 7/7/7 (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2012
NDA 078376 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) GILDAGIA (PH HEALTH) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 091204 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) WERA (NOVAST LABS LTD) APPROVAL= AP YEAR= 2012
NDA 091323 (pdf not found) INN (NORETHINDRONE) JENCYCLA (LUPIN LTD) APPROVAL= AP YEAR= 2013
NDA 200961 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (NOVAST LABS) APPROVAL= AP YEAR= 2013
NDA 200980 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (XIROMED) APPROVAL= AP YEAR= 2013
NDA 201483 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (XIROMED) APPROVAL= AP YEAR= 2013
NDA 201510 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) PIRMELLA 7/7/7 (LUPIN LTD) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 201512 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) PIRMELLA 1/35 (LUPIN LTD) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 201886 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) VYFEMLA (LUPIN) APPROVAL= AP YEAR= 2013
NDA 202014 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (NOVAST LABS) APPROVAL= AP YEAR= 2013
NDA 202260 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 203006 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 203371 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2014
NDA 200897 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (XIROMED) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 202086 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (XIROMED) APPROVAL= AP YEAR= 2015
NDA 200486 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (MYLAN LABS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 200488 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (MYLAN LABS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 200489 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (MYLAN LABS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 203413 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) CYCLAFEM 0.5/35 (PH HEALTH) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 203448 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) KAITLIB FE (LUPIN) APPROVAL= AP YEAR= 2015
NDA 091332 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (LUPIN) APPROVAL= AP YEAR= 2016
NDA 206807 (pdf not found) INN (NORETHINDRONE) NORETHINDRONE (NAARI PTE) APPROVAL= AP YEAR= 2016
NDA 207054 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NYLIA 7/7/7 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207055 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) CYONANZ (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207056 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NYLIA 1/35 (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207304 (pdf not found) INN (NORETHINDRONE) INCASSIA (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 206864 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL (NAARI PTE) APPROVAL= AP YEAR= 2017
NDA 207066 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE (NAARI PTE) APPROVAL= AP YEAR= 2017
NDA 207535 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) NEXESTA FE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2017
NDA 207585 (pdf not found) INN (ETHINYL ESTRADIOL ; NORETHINDRONE) RHUZDAH (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 216796 (pdf not found) INN (NORETHINDRONE) EMZAHH (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2023