e-Drug3D

2035

M FEXINIDAZOLE

INN
FEXINIDAZOLE

cas 62351-99-9

CLASS

ANTIPARASITIC
ANTIPROTOZOAL
NITROIMIDAZOLE ANTIMICROBIAL
TREATMENT OF HUMAN AFRICAN TRYPANOSOMIASIS (HAT) DUE TO TRYPANOSOMA BRUCEI GAMBIENSE

ROUTE (list)

ATC code

P01CA03

PK parameters

Tmax 4 HOUR
PPB 41 PERCENT
t1/2 16 HOUR

Target

DrugCentral

Unknown

Download SDF file

1H-Imidazole, 1-methyl-2-[[4-(methylsulfinyl)phenoxy]methyl]-5-nitro- (9CI, ACI)

Formula:
C12H13N3O4S

Calculated chemical properties:

MW 295.32
NB_atoms 20
XLogP 1.64
PSA 82.131
NB_HD 0
NB_HA 6
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
-

Other links:

e-Drug3D

2034

FEXINIDAZOLE

INN
FEXINIDAZOLE

cas 59729-37-2

CLASS

ANTIPARASITIC
ANTIPROTOZOAL
NITROIMIDAZOLE ANTIMICROBIAL
TREATMENT OF HUMAN AFRICAN TRYPANOSOMIASIS (HAT) DUE TO TRYPANOSOMA BRUCEI GAMBIENSE

ROUTE (list)

ORAL

ATC code

P01CA03

PK parameters

Tmax 4 HOUR
VD 3222 LITER
Cl 161 LITER / HOUR
PPB 98 PERCENT
t1/2 15 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

DrugCentral

Unknown

Download SDF file

1H-Imidazole, 1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro- (9CI, ACI)

Formula:
C12H13N3O3S

Calculated chemical properties:

MW 279.32
NB_atoms 19
XLogP 2.63
PSA 65.69
NB_HD 0
NB_HA 5
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
NDA 214429 (label) INN (FEXINIDAZOLE) FEXINIDAZOLE (SANOFI) APPROVAL= AP YEAR= 2021 NEWMOLECULARENTITY