e-Drug3D

1601

cas 10040-45-6

CLASS

METABOLISM
LAXATIVE
HYDROLYZED BY COLONIC BACTERIA
STIMULATE COLONIC PERISTALSIS

ROUTE (list)

ORAL

PK parameters

Tmax 7 HOUR
t1/2 7.4 HOUR

MW 437.45
NB_atoms 29
XLogP 2.63
PSA 140.107
NB_HD 2
NB_HA 9
fsp3 0.06
Lipinski(0=no;1=yes) 0

FDA
NDA 202535 (label) INN (CITRIC ACID ; MAGNESIUM OXIDE ; SODIUM PICOSULFATE) PREPOPIK (FERRING PHARMS INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 205743 (pdf not found) INN (CITRIC ACID ; MAGNESIUM OXIDE ; SODIUM PICOSULFATE) CITRIC ACID; MAGNESIUM OXIDE; SODIUM PICOSULFATE (PAR PHARM INC) APPROVAL= TA YEAR= 2016
NDA 209589 (label) INN (CITRIC ACID ; MAGNESIUM OXIDE ; SODIUM PICOSULFATE) CLENPIQ (FERRING PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 212789 (pdf not found) INN (CITRIC ACID ; MAGNESIUM OXIDE ; SODIUM PICOSULFATE) SODIUM PICOSULFATE, MAGNESIUM OXIDE AND ANHYDROUS CITRIC ACID (HETERO LABS LTD V) APPROVAL= AP YEAR= 2022

e-Drug3D

1608

cas 603-41-8

CLASS

METABOLISM
LAXATIVE
STIMULATE COLONIC PERISTALSIS

ROUTE (list)

-

PK parameters

MW 277.31
NB_atoms 21
XLogP 3.67
PSA 52.846
NB_HD 2
NB_HA 3
fsp3 0.06
Lipinski(0=no;1=yes) 1

FDA
-