1348
GLUCOCORTICOID
COTICOSTEROIDS
AGONIST
PSORIASIS
TOPICAL
ATC code
A07EA04
C05AA05
D07AC01
D07XC01
H02AB01
R01AD06
R03BA04
S01BA06
S01CB04
S02BA07
S03BA03
D07CC01
S01CA05
S03CA06
D07BC01
S01BB04
TARGET GLUCOCORTICOID RECEPTOR
Glucocorticoid receptor UNIPROT P04150 NR3C1
Formula:
C29H33FO6
Calculated chemical properties:
NB_atoms 36
XLogP 3.76
PSA 81.698
NB_HD 2
NB_HA 6
fsp3 0.55
Lipinski(0=no;1=yes) 1
NDA 017244 (pdf not found) INN (BETAMETHASONE BENZOATE) UTICORT (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 017528 (pdf not found) INN (BETAMETHASONE BENZOATE) UTICORT (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018089 (pdf not found) INN (BETAMETHASONE BENZOATE) UTICORT (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016998 (pdf not found) INN (BETAMETHASONE BENZOATE) UTICORT (PARKE DAVIS) APPROVAL= AP YEAR= 1974 DISCONTINUED
304
DERMATOLOGICALS
GLUCOCORTICOID
ANTIPSORIATIC
ANTIINFLAMMATORY
CORTICOSTEROID
ANTIPRURITIC
VASOCONSTRICTIVE PROPERTIES
ORAL TOPICAL
ATC code
A07EA04
C05AA05
D07AC01
D07XC01
H02AB01
R01AD06
R03BA04
S01BA06
S01CB04
S02BA07
S03BA03
D07CC01
S01CA05
S03CA06
D07BC01
S01BB04
VD 84.5 LITER (65 KILOGRAM)
Cl 10.9 LITER / HOUR (65 KILOGRAM)
PPB 64 PERCENT
t1/2 5.6 HOUR
TARGET GLUCOCORTICOID RECEPTOR
Glucocorticoid receptor UNIPROT P04150 NR3C1
Formula:
C22H29FO5
Calculated chemical properties:
NB_atoms 28
XLogP 1.90
PSA 80.652
NB_HD 3
NB_HA 5
fsp3 0.73
Lipinski(0=no;1=yes) 1
NDA 014762 (pdf not found) INN (BETAMETHASONE) CELESTONE (SCHERING) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012657 (pdf not found) INN (BETAMETHASONE) CELESTONE (SCHERING) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 014215 (label) INN (BETAMETHASONE) CELESTONE (MERCK SHARP DOHME) APPROVAL= AP YEAR= 1964 DISCONTINUED