e-Drug3D

108

cas 50-23-7

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
ADRENAL INSUFFICIENCY (DRUG FOR RARE DISEASE IN EUROPE)

ROUTE (list)

ORAL TOPICAL VAGINAL INJECTION OTIC RECTAL OPHTHALMIC

PK parameters

VD 24.7 LITER (65 KILOGRAM)
Cl 22.2 LITER / HOUR (65 KILOGRAM)
PPB 80 PERCENT
t1/2 1.6 HOUR

TARGET GLUCOCORTICOID RECEPTOR

PDB
2VDY (CRYSTAL STRUCTURE OF THE REACTIVE LOOP CLEAVED CORTICOSTEROID BINDING GLOBULIN COMPLEXED WITH CORTISOL)

Ligand code = HCY (link to the list of PDB complexes)

Download experimental 3D coordinates of HCY with added hydrogens

MW 362.45
NB_atoms 26
XLogP 1.78
PSA 86.016
NB_HD 3
NB_HA 5
fsp3 0.81
Lipinski(0=no;1=yes) 1

FDA
NDA 009585 (pdf not found) INN (HYDROCORTISONE) CORT-DOME (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009796 (pdf not found) INN (HYDROCORTISONE) CORTRIL (PFIPHARMECS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009864 (pdf not found) INN (HYDROCORTISONE) CORTEF (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009895 (pdf not found) INN (HYDROCORTISONE) CORT-DOME (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 040097 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) HYDROCORTISONE AND ACETIC ACID (BAUSCH AND LOMB) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060730 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) OTOCORT (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061816 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) OTOBIONE (SCHERING) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062381 (pdf not found) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN & POLYMYXIN B SULFATES & BACITRACIN ZINC & HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062389 (pdf not found) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) ZINC BACITRACIN,NEOMYCIN SULFATE,POLYMYXIN B SULFATE & HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062394 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN SULFATE-POLYMYXIN B SULFATE-HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062399 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) OTICAIR (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062521 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) OTOCORT (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062617 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN SULFATE, POLYMYXIN B SULFATE & HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062623 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN SULFATE-POLYMYXIN B SULFATE-HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080395 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080438 (pdf not found) INN (HYDROCORTISONE) HC #1 (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080452 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (EVERYLIFE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080456 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (INGRAM PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080624 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ELKINS SINN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080732 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (INWOOD LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080781 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (IMPAX LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080848 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ALTANA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083219 (pdf not found) INN (HYDROCORTISONE) EPICORT (BLULINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083947 (pdf not found) INN (HYDROCORTISONE ; UREA) CALMURID HC (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084055 (pdf not found) INN (HYDROCORTISONE) ELDECORT (VALEANT PHARM INTL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084059 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (G AND W LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084243 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084247 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084573 (pdf not found) INN (HYDROCORTISONE) DERMACORT (SOLVAY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084737 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084738 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084747 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084748 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084969 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084970 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085026 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085028 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085191 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TEVA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085527 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (SYOSSET) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085662 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085663 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PERRIGO NEW YORK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085805 (pdf not found) INN (HYDROCORTISONE) AEROSEB-HC (ALLERGAN HERBERT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086170 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (STIEFEL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086462 (pdf not found) INN (HYDROCORTISONE) DERMACORT (SOLVAY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086823 (pdf not found) INN (HYDROCORTISONE) H-CORT (PHARM ASSOC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086824 (pdf not found) INN (HYDROCORTISONE) H-CORT (PHARM ASSOC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087136 (pdf not found) INN (HYDROCORTISONE) FLEXICORT (WESTWOOD SQUIBB) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087532 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087838 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088027 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088029 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088215 (pdf not found) INN (HYDROCORTISONE) PENECORT (ALLERGAN HERBERT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088217 (pdf not found) INN (HYDROCORTISONE) PENECORT (ALLERGAN HERBERT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088539 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ROXANE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088667 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088668 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088669 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088670 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088712 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088845 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PHARMADERM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089413 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PHARMADERM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089577 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089578 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089579 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089580 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089581 (pdf not found) INN (HYDROCORTISONE SODIUM PHOSPHATE) HYDROCORTISONE SODIUM PHOSPHATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089754 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ALPHARMA US PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 008506 (pdf not found) INN (HYDROCORTISONE) HYDROCORTONE (MERCK) APPROVAL= AP YEAR= 1952 DISCONTINUED
NDA 008697 (label) INN (HYDROCORTISONE) CORTEF (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1952
NDA 009127 (pdf not found) INN (HYDROCORTISONE) CORTRIL (PFIZER) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 009659 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PANRAY) APPROVAL= AP YEAR= 1955 DISCONTINUED
NDA 009866 (label) INN (HYDROCORTISONE SODIUM SUCCINATE) SOLU-CORTEF (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1955
NDA 050168 (label) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CORTISPORIN (MONARCH PHARMS) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 012052 (pdf not found) INN (HYDROCORTISONE SODIUM PHOSPHATE) HYDROCORTONE (MERCK) APPROVAL= AP YEAR= 1960 DISCONTINUED
NDA 012770 (label) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) VOSOL HC (SAPTALIS PHARMS) APPROVAL= AP YEAR= 1961
NDA 050169 (label) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CORTISPORIN (MONARCH PHARMS) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 050237 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE) NEO-CORT-DOME (BAYER PHARMS) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 016199 (label) INN (HYDROCORTISONE) CORTENEMA (ANI PHARMS) APPROVAL= AP YEAR= 1966
NDA 050238 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE ; NEOMYCIN SULFATE) NEO-CORT-DOME (BAYER PHARMS) APPROVAL= AP YEAR= 1966 DISCONTINUED
NDA 050416 (label) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CORTISPORIN (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 080425 (pdf not found) INN (HYDROCORTISONE) TEXACORT (MISSION PHARMA) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 080426 (pdf not found) INN (HYDROCORTISONE) CETACORT (BAUSCH) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 009176 (pdf not found) INN (HYDROCORTISONE) CORTRIL (PFIZER GLOBAL) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 061606 (pdf not found) INN (HYDROCORTISONE ; POLYMYXIN B SULFATE) PYOCIDIN (FOREST LABS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080355 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (WATSON LABS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080400 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TEVA) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080442 (pdf not found) INN (HYDROCORTISONE) NUTRACORT (BAUSCH) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080443 (pdf not found) INN (HYDROCORTISONE) NUTRACORT (DOW PHARM) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080472 (pdf not found) INN (HYDROCORTISONE) HYTONE (VALEANT INTL) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080473 (pdf not found) INN (HYDROCORTISONE) HYTONE (VALEANT INTL) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080474 (pdf not found) INN (HYDROCORTISONE) HYTONE (DERMIK LABS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080568 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FERRANTE) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080344 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (WHITEWORTH TOWN PLSN) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080481 (pdf not found) INN (HYDROCORTISONE) HC HYDROCORTISONE (C AND M PHARMA) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080482 (pdf not found) INN (HYDROCORTISONE) HC HYDROCORTISONE (C AND M PHARMA) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080483 (pdf not found) INN (HYDROCORTISONE) HI-COR (C AND M PHARMA) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080496 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (WHITEWORTH TOWN PLSN) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080706 (pdf not found) INN (HYDROCORTISONE) ALA-CORT (CROWN LABS) APPROVAL= AP YEAR= 1973
NDA 083011 (pdf not found) INN (HYDROCORTISONE) PROCTOCORT (MONARCH PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083140 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (NEXGEN PHARMA INC) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083201 (pdf not found) INN (HYDROCORTISONE) ALA-CORT (CROWN LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083231 (pdf not found) INN (HYDROCORTISONE) ALA-SCALP (LEGACY) APPROVAL= AP YEAR= 1973
NDA 083365 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080642 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (SANDOZ) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 083999 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (BARR) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 050479 (label) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CORTISPORIN (MONARCH PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 060613 (label) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CASPORYN HC (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1975
NDA 080692 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FOUGERA PHARMS) APPROVAL= AP YEAR= 1975
NDA 080693 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FOUGERA PHARMS INC) APPROVAL= AP YEAR= 1976
NDA 084698 (pdf not found) INN (HYDROCORTISONE) NUTRACORT (HEALTHPOINT) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085070 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085027 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PADAGIS US) APPROVAL= AP YEAR= 1977
NDA 085492 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) ACETIC ACID W/ HYDROCORTISONE (KV PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085282 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (MERICON) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085733 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (IVAX PHARMS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085928 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (ABBOTT) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085929 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085930 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085931 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085932 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (HOSPIRA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085982 (pdf not found) INN (HYDROCORTISONE) HYDRO-RX (X GEN PHARMS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086008 (pdf not found) INN (HYDROCORTISONE ; UREA) ALPHADERM (BIOGLAN) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086079 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (AMBIX) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086080 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (AMBIX) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086155 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TARO) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086257 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086271 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (AMBIX) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086272 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (AMBIX) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 050272 (pdf not found) INN (HYDROCORTISONE ; TETRACYCLINE HYDROCHLORIDE) ACHROMYCIN (LEDERLE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086844 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) ORLEX HC (WARNER CHILCOTT) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062302 (pdf not found) INN (HYDROCORTISONE ; POLYMYXIN B SULFATE) OTOBIOTIC (SCHERING) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086535 (pdf not found) INN (HYDROCORTISONE) ACTICORT (BAKER NORTON) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086619 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087457 (pdf not found) INN (HYDROCORTISONE) SYNACORT (BAUSCH) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087458 (pdf not found) INN (HYDROCORTISONE) SYNACORT (BAUSCH) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087459 (pdf not found) INN (HYDROCORTISONE) SYNACORT (BAUSCH) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087567 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087568 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087569 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 080459 (pdf not found) INN (HYDROCORTISONE) ELDECORT (VALEANT PHARM INTL) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 080489 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ALTANA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 085025 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PADAGIS US) APPROVAL= AP YEAR= 1982
NDA 086154 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TARO) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086256 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TARO) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087143 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) ACETASOL HC (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087315 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087317 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087644 (pdf not found) INN (HYDROCORTISONE) NUTRACORT (DOW PHARM) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087796 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087834 (pdf not found) INN (HYDROCORTISONE) H-CORT (TORCH) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088041 (pdf not found) INN (HYDROCORTISONE) BALNEOL-HC (SOLVAY) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062423 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (SANDOZ) APPROVAL= AP YEAR= 1983
NDA 087489 (pdf not found) INN (HYDROCORTISONE) GLYCORT (HERAN) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 087795 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1983
NDA 088039 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (USL PHARMA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088061 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (USL PHARMA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088082 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PADDOCK LLC) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088214 (pdf not found) INN (HYDROCORTISONE) PENECORT (ALLERGAN HERBERT) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088216 (pdf not found) INN (HYDROCORTISONE) PENECORT (ALLERGAN HERBERT) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088250 (pdf not found) INN (HYDROCORTISONE) ANUSOL HC (SALIX PHARMS) APPROVAL= AP YEAR= 1984
NDA 088799 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TARO) APPROVAL= AP YEAR= 1984
NDA 062488 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (SANDOZ) APPROVAL= AP YEAR= 1985
NDA 088138 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE IN ABSORBASE (CMP PHARMA INC) APPROVAL= AP YEAR= 1985
NDA 088759 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) HYDROCORTISONE AND ACETIC ACID (TARO) APPROVAL= AP YEAR= 1985
NDA 089066 (pdf not found) INN (HYDROCORTISONE) STIE-CORT (PADAGIS US) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089074 (pdf not found) INN (HYDROCORTISONE) STIE-CORT (PADAGIS US) APPROVAL= AP YEAR= 1985
NDA 089024 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TARO) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089414 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FOUGERA PHARMS INC) APPROVAL= AP YEAR= 1986
NDA 062822 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) PEDIOTIC (MONARCH PHARMS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 088842 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (PHARMADERM) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062874 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (SANDOZ) APPROVAL= AP YEAR= 1988
NDA 087427 (pdf not found) INN (HYDROCORTISONE) NOGENIC HC (IVAX PHARMS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089495 (pdf not found) INN (HYDROCORTISONE) BETA-HC (BETA DERMAC) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089682 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089704 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (NASKA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089705 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (NASKA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089706 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (NASKA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089273 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TOPIDERM) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 081271 (pdf not found) INN (HYDROCORTISONE) TEXACORT (MISSION PHARMA) APPROVAL= AP YEAR= 1992
NDA 081203 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FOUGERA PHARMS INC) APPROVAL= AP YEAR= 1993
NDA 074171 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (TEVA PHARMS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 064053 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 1995
NDA 064068 (pdf not found) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES, BACITRACIN ZINC AND HYDROCORTISONE (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 1995
NDA 040168 (label) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) HYDROCORTISONE AND ACETIC ACID (WOCKHARDT) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064065 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) OTICAIR (BAUSCH AND LOMB INC) APPROVAL= AP YEAR= 1996
NDA 020805 (label) INN (CIPROFLOXACIN HYDROCHLORIDE ; HYDROCORTISONE) CIPRO HC (SANDOZ) APPROVAL= AP YEAR= 1998
NDA 040247 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075172 (pdf not found) INN (HYDROCORTISONE) COLOCORT (CHARTWELL) APPROVAL= AP YEAR= 1999
NDA 040310 (label) INN (HYDROCORTISONE) HYDROCORTISONE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040351 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040417 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 040503 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065216 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (SAPTALIS PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 040609 (pdf not found) INN (ACETIC ACID GLACIAL ; HYDROCORTISONE) HYDROCORTISONE AND ACETIC ACID (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2006
NDA 040666 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) A-HYDROCORT (HOSPIRA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065219 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (SCIEGEN PHARMS) APPROVAL= AP YEAR= 2006
NDA 040646 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (IMPAX LABS INC) APPROVAL= AP YEAR= 2007
NDA 040761 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 022436 (label) INN (ACYCLOVIR ; HYDROCORTISONE) XERESE (BAUSCH) APPROVAL= AP YEAR= 2009
NDA 040879 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (RISING) APPROVAL= AP YEAR= 2010
NDA 065213 (pdf not found) INN (BACITRACIN ZINC ; HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES, BACITRACIN ZINC AND HYDROCORTISONE (SCIEGEN PHARMS) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 207029 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (STRIDES PHARMA) APPROVAL= AP YEAR= 2017
NDA 203804 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ENCUBE) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 203810 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (ENCUBE) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 213876 (label) INN (HYDROCORTISONE) ALKINDI SPRINKLE (ETON) APPROVAL= AP YEAR= 2020
NDA 214649 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2023
NDA 214050 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (CIPLA) APPROVAL= AP YEAR= 2024
NDA 217160 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (HIBROW HLTHCARE) APPROVAL= AP YEAR= 2024
NDA 217881 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2025
NDA 218980 (label) INN (HYDROCORTISONE) KHINDIVI (ETON) APPROVAL= AP YEAR= 2025
NDA 217735 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (AMNEAL) APPROVAL= AP YEAR= 2025
NDA 217803 (pdf not found) INN (HYDROCORTISONE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE (AMNEAL) APPROVAL= AP YEAR= 2025
NDA 218273 (pdf not found) INN (CIPROFLOXACIN HYDROCHLORIDE ; HYDROCORTISONE) CIPROFLOXACIN HYDROCHLORIDE AND HYDROCORTISONE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2025
NDA 217191 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2026
NDA 219856 (pdf not found) INN (HYDROCORTISONE SODIUM SUCCINATE) HYDROCORTISONE SODIUM SUCCINATE (APOTEX) APPROVAL= AP YEAR= 2026
NDA 220329 (pdf not found) INN (HYDROCORTISONE) HYDROCORTISONE (APPCO) APPROVAL= AP YEAR= 2026

e-Drug3D

109

cas 50-03-3

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
RAPIDLY HYDROLYZED IN HYDROCORTISONE

ROUTE (list)

TOPICAL INJECTION OPHTHALMIC OTIC RECTAL

PK parameters

MW 404.49
NB_atoms 29
XLogP 2.35
PSA 91.799
NB_HD 2
NB_HA 6
fsp3 0.78
Lipinski(0=no;1=yes) 1

FDA
NDA 080419 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (CENCI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009018 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTONE (MERCK) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009164 (pdf not found) INN (HYDROCORTISONE ACETATE) CORTRIL (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060610 (pdf not found) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE) NEO-CORTEF (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060612 (pdf not found) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE) NEO-CORTEF (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060731 (pdf not found) INN (BACITRACIN ; HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) BACITRACIN-NEOMYCIN-POLYMYXIN W/ HYDROCORTISONE ACETATE (ALTANA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061049 (pdf not found) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE) NEO-CORTEF (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 081274 (pdf not found) INN (HYDROCORTISONE ACETATE) HEMSOL-HC (ABLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083759 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085214 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086052 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086207 (pdf not found) INN (HYDROCORTISONE ACETATE) DRICORT (INGRAM PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089914 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 008228 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTONE (MERCK) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 008917 (pdf not found) INN (HYDROCORTISONE ACETATE) CORTEF ACETATE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050202 (pdf not found) INN (CHLORAMPHENICOL ; HYDROCORTISONE ACETATE) CHLOROMYCETIN HYDROCORTISONE (PARKEDALE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050201 (pdf not found) INN (CHLORAMPHENICOL ; HYDROCORTISONE ACETATE ; POLYMYXIN B SULFATE) OPHTHOCORT (PARKEDALE) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 050356 (label) INN (COLISTIN SULFATE ; HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE ; THONZONIUM BROMIDE) COLY-MYCIN S (PH HEALTH) APPROVAL= AP YEAR= 1962
NDA 050218 (label) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) CORTISPORIN (MONARCH PHARMS) APPROVAL= AP YEAR= 1963 DISCONTINUED
NDA 060751 (pdf not found) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE) NEO-CORTEF (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1965 DISCONTINUED
NDA 060188 (pdf not found) INN (HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE) COR-OTICIN (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 061016 (pdf not found) INN (HYDROCORTISONE ACETATE ; OXYTETRACYCLINE HYDROCHLORIDE) TERRA-CORTRIL (PFIZER) APPROVAL= AP YEAR= 1969 DISCONTINUED
NDA 080505 (pdf not found) INN (HYDROCORTISONE ACETATE) CARMOL HC (FOUGERA PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083205 (pdf not found) INN (HYDROCORTISONE ACETATE) ORABASE HCA (COLGATE) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083213 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PRAMOSONE (FERNDALE LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083739 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (BEL MAR) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 080828 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (FERA PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 083778 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PRAMOSONE (LEGACY) APPROVAL= AP YEAR= 1976
NDA 009378 (pdf not found) INN (HYDROCORTISONE ACETATE) CORTEF ACETATE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085368 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PRAMOSONE (LEGACY) APPROVAL= AP YEAR= 1977
NDA 085979 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PRAMOSONE (LEGACY) APPROVAL= AP YEAR= 1978
NDA 085980 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PRAMOSONE (LEGACY) APPROVAL= AP YEAR= 1978
NDA 085981 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (X GEN PHARMS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086195 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) PROCTOFOAM HC (MYLAN SPECIALITY LP) APPROVAL= AP YEAR= 1978
NDA 083128 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (WATSON LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086457 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) EPIFOAM (MYLAN SPECIALITY LP) APPROVAL= AP YEAR= 1979
NDA 009637 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 062166 (pdf not found) INN (BACITRACIN ZINC ; HYDROCORTISONE ACETATE ; NEOMYCIN SULFATE ; POLYMYXIN B SULFATE) BACITRACIN-NEOMYCIN-POLYMYXIN W/ HYDROCORTISONE ACETATE (PADAGIS US) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086050 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (PUREPAC PHARM) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 017351 (label) INN (HYDROCORTISONE ACETATE) CORTIFOAM (VIATRIS) APPROVAL= AP YEAR= 1982
NDA 089440 (pdf not found) INN (HYDROCORTISONE ACETATE ; PRAMOXINE HYDROCHLORIDE) HYDROCORTISONE ACETATE 1% AND PRAMOXINE HYDROCHLORIDE 1% (GENUS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089472 (pdf not found) INN (HYDROCORTISONE ACETATE) U-CORT (SUN PHARMA CANADA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040259 (pdf not found) INN (HYDROCORTISONE ACETATE) HYDROCORTISONE ACETATE (IMPERIUM) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040396 (pdf not found) INN (HYDROCORTISONE ACETATE) MICORT-HC (LEGACY) APPROVAL= AP YEAR= 2001
NDA 040398 (pdf not found) INN (HYDROCORTISONE ACETATE) MICORT-HC (LEGACY) APPROVAL= AP YEAR= 2002 DISCONTINUED

e-Drug3D

110

cas 57524-89-7

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
RAPIDLY HYDROLYZED IN HYDROCORTISONE

ROUTE (list)

TOPICAL

PK parameters

MW 446.56
NB_atoms 32
XLogP 3.52
PSA 88.27
NB_HD 2
NB_HA 6
fsp3 0.81
Lipinski(0=no;1=yes) 1

FDA
NDA 017950 (label) INN (HYDROCORTISONE VALERATE) WESTCORT (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018726 (label) INN (HYDROCORTISONE VALERATE) WESTCORT (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 074489 (label) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075042 (label) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 1998
NDA 075043 (label) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 1998
NDA 075666 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075085 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 211129 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 211750 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210307 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (LUPIN) APPROVAL= AP YEAR= 2019
NDA 211764 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2020
NDA 213724 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2021
NDA 211047 (pdf not found) INN (HYDROCORTISONE VALERATE) HYDROCORTISONE VALERATE (ENCUBE ETHICALS) APPROVAL= AP YEAR= 2021

e-Drug3D

111

cas 13609-67-1

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
RAPIDLY HYDROLYZED IN HYDROCORTISONE

ROUTE (list)

TOPICAL

PK parameters

MW 432.54
NB_atoms 31
XLogP 3.13
PSA 88.225
NB_HD 2
NB_HA 6
fsp3 0.80
Lipinski(0=no;1=yes) 1

FDA
NDA 018795 (pdf not found) INN (HYDROCORTISONE BUTYRATE) LOCOID (YAMANOUCHI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 019106 (pdf not found) INN (HYDROCORTISONE BUTYRATE) LOCOID (YAMANOUCHI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 019819 (pdf not found) INN (HYDROCORTISONE BUTYRATE) LOCOID (YAMANOUCHI) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018514 (label) INN (HYDROCORTISONE BUTYRATE) LOCOID (BAUSCH) APPROVAL= AP YEAR= 1982
NDA 018652 (label) INN (HYDROCORTISONE BUTYRATE) LOCOID (PRECISION DERMAT) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 019116 (label) INN (HYDROCORTISONE BUTYRATE) LOCOID (BAUSCH) APPROVAL= AP YEAR= 1987
NDA 020769 (label) INN (HYDROCORTISONE BUTYRATE) LOCOID LIPOCREAM (PRECISION DERMAT) APPROVAL= AP YEAR= 1997
NDA 076364 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (TARO PHARM INDS) APPROVAL= AP YEAR= 2004
NDA 076842 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (TARO) APPROVAL= AP YEAR= 2004
NDA 076654 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (TARO PHARM INDS) APPROVAL= AP YEAR= 2005
NDA 022076 (label) INN (HYDROCORTISONE BUTYRATE) LOCOID (BAUSCH) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 202145 (label) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 205134 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2017
NDA 209556 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (THE J MOLNER) APPROVAL= AP YEAR= 2017
NDA 210209 (pdf not found) INN (HYDROCORTISONE BUTYRATE) HYDROCORTISONE BUTYRATE (LUPIN) APPROVAL= AP YEAR= 2018

e-Drug3D

191

cas 76-47-1

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTI-INFLAMMATORY
CORTICOSTEROID
IMMUNOSUPPRESSIVE AGENTS

ROUTE (list)

TOPICAL

PK parameters

MW 475.61
NB_atoms 34
XLogP 2.67
PSA 93.59
NB_HD 2
NB_HA 7
fsp3 0.81
Lipinski(0=no;1=yes) 1

FDA
NDA 010554 (pdf not found) INN (HYDROCORTAMATE HYDROCHLORIDE) MAGNACORT (PFIZER) APPROVAL= AP YEAR= 1956 NEWMOLECULARENTITY DISCONTINUED

e-Drug3D

1327

cas 508-99-6

CLASS

METABOLISM
GLUCOCORTICOID
AGONIST
ANTI-INFLAMMATORY

ROUTE (list)

ORAL

PK parameters

MW 486.63
NB_atoms 35
XLogP 4.30
PSA 89.714
NB_HD 2
NB_HA 6
fsp3 0.83
Lipinski(0=no;1=yes) 1

FDA
NDA 009900 (pdf not found) INN (HYDROCORTISONE CYPIONATE) CORTEF (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1955 DISCONTINUED

e-Drug3D

1328

cas 72590-77-3

CLASS

DERMATOLOGICALS
AGONIST
GLUCOCORTICOID
ANTI-INFLAMMATORY

ROUTE (list)

TOPICAL

PK parameters

MW 488.60
NB_atoms 35
XLogP 4.09
PSA 92.947
NB_HD 1
NB_HA 7
fsp3 0.79
Lipinski(0=no;1=yes) 1

FDA
NDA 020453 (label) INN (HYDROCORTISONE PROBUTATE) PANDEL (ANI PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED