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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NELARABINE (has an active metabolite)
| NELARABINE | ANTINEOPLASTIC | INTRAVENOUS | Cmax 16.8 MICROMOLAR VD 318.5 LITER PPB 25 PERCENT Cl 315 LITER / HOUR HT 0.3 HOUR SOLUBILITY SLIGHTLY SOLUBLE TO SOLUBLE IN WATER | ADENOSINE DEAMINASE | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT P09884 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT HOMO SAPIENS ENZYME TRANSFERASE | EMA | |||
