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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NEBIVOLOL
| NEBIVOLOL |
CARDIOVASCULAR | ORAL | Tmax 2.75 HOUR VD 715 LITER (65 KILOGRAM) PPB 98 PERCENT Cl 54.6 LITER / HOUR HT 15.5 HOUR | BETA-1 ADRENERGIC RECEPTOR | BETA-2 ADRENERGIC RECEPTOR ANTAGONIST CHEMBL210 BETA-2 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
