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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MIGLUSTAT
| MIGLUSTAT | METABOLISM | ORAL | Tmax 2.25 HOUR F 97 PERCENT VD 94 LITER PPB 0 PERCENT HT 6.5 HOUR SOLUBILITY HIGHLY SOLUBLE IN WATER (> 1000 MILLIGRAM / MILLILITER) | GLUCOSYLCERAMIDE SYNTHASE PDB 2V3D (ACID-BETA-GLUCOSIDASE WITH N-BUTYL-DEOXYNOJIRIMYCIN) LIGAND CODE = NBV (link to the list of PDB complexes) Download experimental 3D coordinates of NBV with added hydrogens | CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR CHEMBL2063 CERAMIDE GLUCOSYLTRANSFERASE Q16739 CERAMIDE GLUCOSYLTRANSFERASE HOMO SAPIENS ENZYME TRANSFERASE | EMA | |||
