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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FULVESTRANT
| FULVESTRANT | ANTINEOPLASTIC | INTRAMUSCULAR | Cmax 46.2 NANOMOLAR VD 260 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 41.4 LITER / HOUR HT 960 HOUR | ESTROGEN RECEPTOR PDB 4J03 (CRYSTAL STRUCTURE OF HUMAN SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH FULVESTRANT) LIGAND CODE = FVS (link to the list of PDB complexes) Download experimental 3D coordinates of FVS with added hydrogens | ESTROGEN RECEPTOR ANTAGONIST CHEMBL2093866 ESTROGEN RECEPTOR P03372 ESTROGEN RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3A NR3A1 | EMA | |||
