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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PIMECROLIMUS
| PIMECROLIMUS | DERMATOLOGICALS | TOPICAL | Cmax 1.72 NANOMOLAR Tmax 4 HOUR PPB 99.5 PERCENT SOLUBILITY INSOLUBLE IN WATER | MACROPHILIN-12 (FKBP-12) | FK506-BINDING PROTEIN 1A INHIBITOR CHEMBL1902 FK506-BINDING PROTEIN 1A P62942 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A HOMO SAPIENS ENZYME ISOMERASE | EMA | |||
