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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NATEGLINIDE
| NATEGLINIDE | METABOLISM | ORAL | Tmax 1 HOUR F 73 PERCENT VD 10 LITER PPB 98 PERCENT Cl 7 LITER / HOUR HT 1.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL | SULFONYLUREA RECEPTOR 1, Q09428 ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 HOMO SAPIENS TRANSPORTER NTPASE ATP BINDING CASSETTE MRP | EMA | |||
