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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVALBUTEROL
| LEVALBUTEROL |
RESPIRATORY SYSTEM | INHALATION | Cmax 12.55 NANOMOLAR HT 4.6 HOUR SOLUBILITY 180 MILLIGRAM / MILLILITER IN WATER | BETA2-ADRENERGIC PDB 2Y04 (TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND PARTIAL AGONIST SALBUTAMOL) LIGAND CODE = 68H (link to the list of PDB complexes) Download experimental 3D coordinates of 68H with added hydrogens | BETA-2 ADRENERGIC RECEPTOR AGONIST CHEMBL210 BETA-2 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
