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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FOMEPIZOLE
| FOMEPIZOLE | VARIOUS | INJECTION | Cmax 300 MICROMOLAR VD 52.6 LITER (65 KILOGRAM) SOLUBILITY SOLUBLE IN WATER | ALCOHOL DEHYDROGENASE PDB 3E4E (HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR 4-METHYLPYRAZOLE) LIGAND CODE = 4PZ (link to the list of PDB complexes) Download experimental 3D coordinates of 4PZ with added hydrogens | ALCOHOL DEHYDROGENASE CLASS I INHIBITOR CHEMBL2363044 ALCOHOL DEHYDROGENASE CLASS I P00325 ALCOHOL DEHYDROGENASE 1B HOMO SAPIENS ENZYME REDUCTASE | EMA | |||
