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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CIDOFOVIR (is an active metabolite) (has an active metabolite)
| CIDOFOVIR | ANTIINFECTIVES | INJECTION | Cmax 70.2 MICROMOLAR VD 26.6 LITER (65 KILOGRAM) PPB 6 PERCENT Cl 8.8 LITER / HOUR HT 2.6 HOUR SOLUBILITY 170 MILLIGRAM / MILLILITER IN WATER | DNA POLYMERASE PDB 5KM8 (HUMAN HISTIDINE TRIAD NUCLEOTIDE BINDING PROTEIN 2 (HHINT2) CIDOFOVIR COMPLEX) LIGAND CODE = L8P (link to the list of PDB complexes) Download experimental 3D coordinates of L8P with added hydrogens | HUMAN HERPESVIRUS 1 DNA POLYMERASE INHIBITOR CHEMBL1872 HUMAN HERPESVIRUS 1 DNA POLYMERASE P04293 DNA POLYMERASE CATALYTIC SUBUNIT HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) ENZYME TRANSFERASE | EMA | |||
