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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BRIMONIDINE
| BRIMONIDINE | SENSORY | OPHTHALMIC TOPICAL | Cmax 0.102 NANOMOLAR Tmax 2 HOUR PPB 29 PERCENT HT 3 HOUR SOLUBILITY SOLUBLE IN WATER 34 MILLIGRAM / MILLILITER | ALPHA-2 ADRENERGIC RECEPTOR | ADRENERGIC RECEPTOR ALPHA-2 AGONIST CHEMBL2095158 ADRENERGIC RECEPTOR ALPHA-2 P08913 ALPHA-2A ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
