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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VALACYCLOVIR (has an active metabolite)
| VALACYCLOVIR | ANTIINFECTIVES | ORAL | Cmax 17.4 MICROMOLAR F 54 PERCENT PPB 15.7 PERCENT SOLUBILITY 174 MILLIGRAM / MILLILITER IN WATER | DNA POLYMERASE PDB 4AQL (HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR) LIGAND CODE = TXC (link to the list of PDB complexes) Download experimental 3D coordinates of TXC with added hydrogens | HUMAN HERPESVIRUS 1 DNA POLYMERASE INHIBITOR CHEMBL1872 HUMAN HERPESVIRUS 1 DNA POLYMERASE P04293 DNA POLYMERASE CATALYTIC SUBUNIT HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) ENZYME TRANSFERASE | EMA | |||
