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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| STAVUDINE
| STAVUDINE | ANTIINFECTIVES | ORAL | Cmax 2.4 MICROMOLAR Tmax 1 HOUR F 86 PERCENT VD 46 LITER PPB 0 PERCENT Cl 35.6 LITER / HOUR HT 1.6 HOUR SOLUBILITY 83 MILLIGRAM / MILLILITER IN WATER | HIV REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE INHIBITOR CHEMBL247 HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE Q72547 REVERSE TRANSCRIPTASE/RNASEH HUMAN IMMUNODEFICIENCY VIRUS 1 ENZYME HYDROLASE | EMA | |||
