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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LANSOPRAZOLE
| LANSOPRAZOLE DEXLANSOPRAZOLE |
METABOLISM | ORAL INTRAVENOUS | Cmax 4.6 MICROMOLAR Tmax 1.7 HOUR F 80 PERCENT VD 15.7 LITER PPB 97 PERCENT Cl 11.1 LITER / HOUR (65 KILOGRAM) HT 1.3 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | (H+,K+) ATPASE | POTASSIUM-TRANSPORTING ATPASE INHIBITOR CHEMBL2095173 POTASSIUM-TRANSPORTING ATPASE P20648 POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 HOMO SAPIENS ENZYME HYDROLASE | EMA | |||
