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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TIZANIDINE
| TIZANIDINE | MUSCULO-SKELETAL SYSTEM | ORAL | F 40 PERCENT VD 156 LITER (65 KILOGRAM) PPB 30 PERCENT Cl 42.9 LITER / HOUR HT 2.5 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | ALPHA-2A ADRENERGIC RECEPTOR | ADRENERGIC RECEPTOR ALPHA-2 AGONIST CHEMBL2095158 ADRENERGIC RECEPTOR ALPHA-2 P08913 ALPHA-2A ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
