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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ANAGRELIDE

ANAGRELIDE


ATC L01XX35

ANTINEOPLASTIC
REDUCES BLOOD PLATELET COUNT
TREATMENT OF ESSENTIAL-THROMBOCYTHAEMIA (ET)

ORAL

Tmax 1 HOUR

F 70 PERCENT

HT 1.5 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

CYCLIC AMP PHOSPHODIESTERASE III

PHOSPHODIESTERASE 3 INHIBITOR CHEMBL2094125 PHOSPHODIESTERASE 3 Q13370 CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B HOMO SAPIENS ENZYME PHOSPHODIESTERASE PDE_3 PDE_3BEMA

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