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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METOCURINE DISCONTINUED
| METOCURINE | NERVOUS SYSTEM | INJECTION | VD 30.6 LITER (65 KILOGRAM) PPB 35 PERCENT Cl 5.7 LITER / HOUR HT 6 HOUR (PMID7023284) | PDB 3PEO (CRYSTAL STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN COMPLEXED WITH METOCURINE) LIGAND CODE = CU9 (link to the list of PDB complexes) Download experimental 3D coordinates of CU9 with added hydrogens | MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST CHEMBL2362997 MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR P02708 ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA HOMO SAPIENS ION CHANNEL LGIC ACH CHRN ALPHA | EMA | |||
